ORANGE Essential Oil for Immune Support

by Cynthe on April 11, 2010

bottle of therapeutic orange essential oil with fresh orangesEssential oils from the orange tree’s flowers, leaves, and rind have powerfully healing effects… remarkably anti-carcinogenic and anti-tumoral, based on it’s high 85%-96% d-limonene chemistry, ORANGE oil has been documented to combat tumor growth in over 50 clinical studies and is being used by individuals as a holistic cancer treatment.

SOURCE: Essential Oils for Physical Health & Well-Being by Linda L. Smith

Clinical trials using d-limonene as a cancer inhibitor have been conducted for well over a decade. D-Limonene and its digestion by-product Perillyl alcohol have been studied at the University of Wisconsin, Indiana University-Purdue University, with a new JAN 2010 clinical trial taking form at the University of Arizona [currently accepting breast cancer volunteers] as well as various medical center trials.

WHY isn’t Orange Essential Oil’s Awesome anti-Cancer Properties Common Knowledge?

My guess…either most oncologists aren’t taught about or aren’t aware of d-Limonene and Perillyl alcohol’s benefits OR there isn’t enough financial incentive to have cancer patients self-administer orange oil for their own recovery as recounted in the personal testimonials at the end of this article.

June 1997 ~ Cancer Chemoprevention and Therapy by Monoterpenes by M N Gould, Department of Human Oncology, University of Wisconsin, Madison USA

“Monoterpenes are found in the essential oils of many plants including fruits, vegetables, and herbs. They prevent the carcinogenesis process at both the initiation and promotion/progression stages. In addition, monoterpenes are effective in treating early and advanced cancers. Monoterpenes such as limonene and perillyl alcohol have been shown to prevent mammary, liver, lung, and other cancers. These compounds have also been used to treat a variety of rodent cancers, including breast and pancreatic carcinomas. In addition, in vitro data suggest that they may be effective in treating neuroblastomas and leukemias.”

Mark Brudnak PhD, ND is a board-certified naturopath, maintaining a natural health consulting practice in Milwaukee, WI. His interesting article “Cancer-Preventing Properties of Essential Oil Monoterpenes D-Limonene and Perillyl Alcohol is well worth reading.

Dr. Brudnak writes “While the MTs [monoterpenes] are indeed used as cleaning (try placing a small amount on the front hubcaps of your car to clean off the black grime) agents, due to their solvent properties, they are far from being poisons. Indeed, nothing could be further from the truth for these wonderful, naturally occurring, and health-promoting substances. While the solvent properties of monoterpenes have been exploited clinically to dissolve gallstones (1), the monoterpenes are also the focus of much investigation in the area of cancer prevention and therapeutics…

always buy the best essential oilsCancer prevention, inhibition, and regression are the most note worthy attributes of the MTs [monoterpenes].

D-limonene (DL) and perillyl alcohol (POH) have been shown to be chemopreventive against mammary (2). liver, lung, UV-induced skin cancers (3), and chemotherapeutic against both experimental mammary and pancreatic tumours. Perillyl alcohol stands out as effective against human pancreatic cancer (4), colon, liver [cancers] (5), to reduce vein graft intimal hyperplasia (6), as chemopreventive against colon carcinogenesis, prostate and lung cancers. (7)

His article has a fascinating discussion of how healthy bodies deal with natural cell mutations ~ for the most part keeping them under control ~  and destroying abnormal cells. With cancers, of course, something has gone seriously wrong. Dr. Brudnak says “The final stage is metastasis. Here, the cancer cells have progressed to the point where they are no longer localized to one ever-growing tumor. They gain the ability to enter the blood vessels (intravasation), move to a different location in the body, stop and exit the blood vessel (extravasation) and establish a new site of tumor development. Eventually, the body becomes riddled with tumors consuming the bulk of available energy. The body is literally eaten alive as evidenced by the cancer associated cachexia (body wasting).

In that dreadfully bleak picture of cancer development, there are some valiantly shining points of light. The MTs [monoterpenes], found in essential oils, are such points of light, offering some hope in the struggle to prevent and treat cancer. The best news is that DL and POH can not only prevent, but also treat cancer. That is to say, the MTs can act before a cancer is established and, in the cases where cancer is already present, they can cause a regression of the tumor.”

essential oil from orange tree's leaves, rind, and flowers have powerfully healing effects

Personal Orange Oil Anti-Cancer Testimonials are Starting to Surface… even though they are anecdotal, these incredible results should NOT be discounted!

An essential oils education group in Arvada, CO reports ORANGE therapeutic-quality essential oil is demonstrating great promise against cancer…helping the body rid itself of cancer. When people are willing to ingest 10ml of orange oil (in capsules) every day […that’s NOT a typo! And it is a lot of Orange essential oil – 2/3 of a 15ml bottle daily], this replicates the amount of limonene in studies which have demonstrated a regression of cancer.

VO writes in her newsletter: “…It’s absolutely amazing that something as simple as orange oil, which is very inexpensive, rubbed over an area of concern, …neat (without dilution), and liberally (6-8 drops  each [application] ), and often, perhaps even several times a daymight hold the key to the challenges with cancer.”

~ While in Japan recently, a woman of about 45 shared she had been told last summer [2009] her uterine cancer had spread throughout her body and she only had a month to live. The doctors said ~ due to her condition ~ they were not able to offer surgery or chemotherapy. After speaking with a Young Living leader there, she took 10ml of orange oil every day, in capsules. She also rubbed [Young Living therapeutic-quality] orange oil, frankincense, myrtle, sandalwood, and tsuga essential oils all over her belly every day, and drank 4-6 oz. NingXia Red [nutritional juice] each day, as well. She is now CANCER FREE!

~ From CD in New Jersey: “My mother-in-law had a grapefruit-sized tumor on her only remaining kidney. Her other kidney had been destroyed by cancer 5 years earlier. The doctors could not treat her because of her deteriorating health, so she began to take 10 ml of orange oil in capsules. She took 2 full capsules every 2 hours for eight hours a day. After 3 months the tumor was gone. She continues to take 1-4 capsules of orange oil and also drinks 2-4 oz. Ningxia Red every day. Her CANCER has NOT returned.”

SOURCE: April 2010 ISHA Aromatherapy Newsletter

Other studies have shown that FRANKINCENSE (Up to 90% Monoterpenes, 12% limonene), MYRTLE, SANDALWOOD, and TSUGA all have excellent inhibition of cancer cells. (Read the Frankincense link for another incredible cancer healing testimonial.)

If you are considering using ORANGE or any other essential oil for your own well-being or for healing from cancer, it’s essential to ONLY use organically grown, AFNOR or EC or ISO certified products for internal and ‘neat’ (non-diluted) topical* applications to assure therapeutic standards. Essential oils are stored in our fatty tissues, one of the reasons they are SO effective as a breast cancer preventative and/or treatment. Those of us who are plump or “well-endowed” will have lots of citrus oil compounds in our tissues if we use those healing oils on a regular basis.

If you are interested in Young Living’s essential oils, please learn how to order from YLO on our BUY THE BEST page or contact me. I’m glad to walk you through the process.

Safety Data: Some people are genetically sensitive to compounds in citrus essential oils. I’m one of those folks (inherited from my father). Citrus oils used daily by those of us, over time (months to years), may cause a sensitivity that creates a very itchy, persistent rash. Suspect it’s a detoxing reaction ~ annoying and bothersome ~ NOT dangerous.

After using LEMON essential oil as a deodorant for several years (a few drops per day), I now cannot use citrus oils directly on my skin, except for my palms & the soles of my feet, without breaking out into a rash under my arms or on the skin surface where it was applied. I can take the citrus oils internally, but they are powerful detoxifiers and occasionally cause a rash that way, too.

ALL citrus essential oils have compounds that may cause sunburn / skin damage with sun exposure, except for GRAPEFRUIT essential oil. This means if you’re applying citrus oils topically, you need to put them “where the sun doesn’t shine” under your clothing or put them on before you go to sleep or when you know you’re going to be inside all day and stay out of the sun for 12 hours after application.

Cynthia Brush, Young Living Oils Distributor #168709Cynthe Brush ~ Certified Clinical (Medical) Aromatherapist, Therapeutic Essential Oils Practitioner & Self-Care Health Educator has used therapeutic essential oils for personal, family, & client health issues since 1999.

Personal Consultations pre-paid on an hourly basis.

Gaia's Pharmacopeia Buy Healing Essential Oils Blends / 100% Natural Botanical Perfumes:
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{ 59 comments… read them below or add one }

Cynthe February 15, 2014 at 10:35 pm

Hello Claramarie,

Glad you found our site.

You will need to put the oil in capsules yourself. Only make the capsules as you are ready to take them. If you do them much in advance, the oils will dissolve the capsules and make a mess!

I use Young Living Essential Oils primarily. If you decide to purchase from Young Living, please use my name: Cynthia Brush and my YLO Distributor Number: 168709 as your referring sponsor. Here’s the on-line sign-up page.

Since you will be using the products to help your body heal, I’d suggest you sign on as a distributor (like I am), which entitles you to a price discount. If you choose monthly Essential Rewards auto-ship ($50-$100/mo orders), you will start accumulating credits for FREE products after three months. (If you introduce others to using Young Living Essential Oils, then you will accumulate credits from their purchases as well.)

An excellent way to use the essential oils internally during your sleep (by-passing digestion) is:
1) Massage your breast(s), morning and evening, with Frankincense and Lavender. Many years ago I heard, first-hand from a woman who healed her breast cancer that way using Frankincense.

2) We have created a handy instructional Frankincense info packet (PDF) describing TWO detailed, easy-to-follow Frankincense protocols. The PDF includes reference links about current research being done with Frankincense cancer therapies in the USA and abroad. The instructional packet costs: $19.99. We accept credit card payments over the phone: 707-542-0280 (9am-9pm California time) or I can email a Paypal invoice, whichever you prefer.

Start slowly. Observe how your body reacts and ramp up the oils concentration over a few weeks. However, when the body is impacted with cancer, my understanding is one needs to use the oils in a concentrated way to make the biological environment vibrant. With concentrated doses you may have some detoxing reactions (some nausea, fatigue, perhaps headaches, etc….but nothing like doing chemo) as your body works to heal itself.

If you search our site for the term ‘cancer,’ you will come across articles with other dietary and lifestyle suggestions for healing support. I have additional information about other Frankincense protocols and a nutritional superfood, I recently learned about, that was developed specifically to reverse cancer to restore health and well-being. Email me directly, if you are interested.

~ Cynthe

Certified Clinical (Medical) Aromatherapist

Timothy Durkin February 21, 2014 at 7:49 pm


My name is TimDurkin and live in Sacramento, California. Recently I have been introduced to “essential oils”. Especially Orange oil, Frankincense, and Sandalwood. I am currently undergoing chemotherapy for bone cancer, and am using the above named oils via a diffuser. TIM DURKIN

Cynthe February 21, 2014 at 10:34 pm

Tim ~ Glad you found our site. Best wishes to you in dealing with this challenging health issue. Orange, Frankincense, and Sandalwood essential oils are all wonderfully immune supportive and uplifting when diffused. How long have you been using essential oils?

jamie frisk June 24, 2014 at 2:48 pm

Is the orange oil good for Lung cancer?

Cynthe June 24, 2014 at 5:42 pm

Hi Jamie ~ We share what others have done to support their immune systems with essential oils. By USA law, I am not permitted to say an oil is definitively good for a particular cancer in a specific individual. However, something important to look into is using hemp (cannabis) oil….some folks have had GREAT success in ridding their bodies of cancer. Here are some of their stories. I’d definitely give this a try if I were dealing with cancer.

darlene June 25, 2014 at 8:34 am

Is orange oil more potent in limonene then lemon oil? I have precancerous breast cells and massage with lemon, frankincense and sage. I would like to diffuse something as I sleep…suggestions?

Cynthe June 25, 2014 at 9:44 am

Darlene ~ Grapefruit essential oil is the most potent in terms of d-limonene <92%…a very ‘happy’ aroma EO. LOVE it! From one of my reference books, here are the different citrus oils’ d-limonene contents compared: Lemon up to 72% | Lime <65% | Mandarin up to 75% | Orange <90% | Tangerine <80% (Mandarin & Tangerine are both considered very gentle). CAUTIONS: Lemon EO used in concentration or regularly over a long period of time can cause sensitization in some people. I know because it happened to me and my father. AVOID exposure to direct sunlight for up to 12 hours after use for all, except Grapefruit EO.

The citrus EOs would be more economical to diffuse, but that may not be a priority when it comes to your health. Frankincense-Grapefruit combo might be good.

Do look into the hemp / cannibis oil links I posted yesterday. It might clear your body from those cells in no time.

Mya July 17, 2014 at 7:14 am

Hi. What oils can be used for basal cell carcinoma nodule type?

Can they be topical only or do they need to be ingested?

Cynthe July 18, 2014 at 8:25 am

Mya ~ Many pure steam distilled essential oils have anti-tumoral compounds, especially citrus oils (see my prior comment to Darlene). Frankincense, especially Boswellia sacra, is being studied in its effectiveness as a cancer treatment. There are others too, like Ledum, Sandalwood, Tsuga and more. In laboratory studies, some seem more effective than others for different cancers. Also, cannabis indica oil is rather amazing in its healing effects. Please read my comment to Jamie.

For skin cancers, topical application is fine. Organically grown, oils like Young Living’s may be ingested though you will read much advice insisting not to. If you want to know more purchase a good reference book for your library. Or schedule an ‘Aromatherapy For You‘ consultation.

Pankaj July 26, 2014 at 3:21 pm


I would like to know how could the Oil help for fighting tumor in the Brain. Is the oil effective in fighting Brain Cancer. Does it cross the Blood Brain barrier if consumed? Or what could be an effective way for the Oil to reach the Brain and be effective. Thats the challenge we are facing at the moment.


Cynthe July 26, 2014 at 6:39 pm

Pankaj ~ The limonene in pure orange essential oil is effective in fighting tumors. Would have to do a bit of research to see if citrus essential oils cross the blood brain barrier…(will do that as part of our consultation). Both Frankincense and Sandalwood DO cross the blood brain barrier and have compounds effective against tumors, so they may be good options to consider as well.

Thanks for your consultation request/payment. Will review the health history form you completed on your father’s behalf this evening. It is good to know his body is not impacted by chemo / radiation / invasive surgeries and is using natural alternatives. I will email you directly to ask a few more questions and set up a time for us to talk via the phone, tomorrow…if that is a good day for you. Best wishes. Talk to you soon.

Suzanne Thompson August 11, 2014 at 7:39 pm

I was diagnosed with endometrial cancer I’m 2013 and have undergone chemotherapy and radiation. I have recently started studying essential oils but I’m very confused about what to take and how to take it. Can you please guide me in the right direction. I’m not even sure where to start.

Cynthe August 11, 2014 at 9:45 pm

Hello Suzanne ~ Glad you’ve found our site in your search for more info on using essential oils. I’d suggest starting with reading our articles on holistic healing options and lifestyle considerations when dealing with a cancer challenge. Just use the search term: cancer in our search box. Be sure to read the reader comment discussions that follow the articles, because some tips are shared there too.

If this research and reading seems too overwhelming (which we definitely understand after being involved with our daughter-in-law’s experience), we also offer personal paid consultations ‘Aromatherapy For You.’

Amy November 24, 2014 at 6:46 pm

Hello! I am also a YL distributor and my husband has just been diagnosed with pancreatic cancer. I am VERY interested in the orange oil and am actually getting ready to place an order. We have also been using Frankincense topically over his tumor area (unable to do surgery to remove). Is there any information on people using the oils along side of chemotherapy? Will they still work? Thank you for any information!

Cynthe November 24, 2014 at 7:16 pm

Hi Amy ~ My understanding is that most essential oils can be used along with chemotherapy. Was told many years ago an essential oil that ‘might’ negate effects of chemo is grapefruit ~ a powerfully healing essential oil.

You could consider using Frankincense (especially Sacred Frankincense) oil more intensively. Our pamphlet: Frankincense for Immune Support describes two ways to use Frankincense’s powerful immune enhancing effects internally.

And there are several other natural plant based products folks are using to bolster their immune systems, enabling their bodies to heal from various cancer challenges. Best wishes to you and your husband for his recovery.

Dominique Paul Fratkin January 29, 2015 at 3:00 am

Hello Amy,
Do you know any way to get your products in France,
or Europe in general?
My mother lives in Marseille France.
Thank you very much,

Cynthe January 29, 2015 at 8:35 am

Hello Dominique ~ Here’s the link to the European site where you and/or your mother may sign up as customers and purchase essential oils. Please use my full name: Cynthia Brush and YLO Customer #168709, so they can track where you learned about the oils.

deanna February 16, 2015 at 5:53 am

I havea huge thyroid nodule tumor for a long time now which may have turned cancerous im very afraid of invasive procedures would the orange oil help me where do I order from god bless you

Cynthe February 16, 2015 at 7:08 am

Hi Deanna ~ Have you been diagnosed by a doctor, yet? At the least, you should have that done. There are other maladies that can cause enlargement of the thyroid. A healthy thyroid is crucial for our well-being, so please find out what really may be going on.

I completely understand your fear of invasive procedures, especially if there are other effective options….which there are. Please go back through the comments on this article and read the info shared with Darlene and Jamie. Those are options I would definitely use myself.

If you want to use citrus EO, then choose GRAPEFRUIT for both internal and external applications based on the woman’s testimonial in the article. My concern is the photo-sensitivity of citrus oils…mentioned in my comments to Darlene.

Another excellent option is a highly regarded detox herbal tea made by FlorEssence (available on-line). I highly recommend reading this book and using this gentle herbal tea. From all the testimonials in the book and on-line, the tea supports the immune system to correct MANY health issues, even serious ones. My husband and I have read the book and are now using the tea for our own well-being.

Best wishes for your return to vibrant health!

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